Open AccessResting state fMRI in pre-surgical brain mapping. Literature review
Author(s) -
А. С. Смирнов,
Maxim Sharaev,
Tatiana Melnikova-Pitskhelauri,
V Iu Zhukov,
Andrey Bykanov,
Е. В. Шарова,
E L Pogosbekyan,
A M Turkin,
Л. М. Фадеева,
Д. И. Пицхелаури,
Valery Kornienko,
Igor Pronin
Publication year - 2018
Publication title -
medicinskaâ vizualizaciâ
Language(s) - English
Resource type - Journals
eISSN - 2408-9516
pISSN - 1607-0763
DOI - 10.24835/1607-0763-2018-5-6-13
Subject(s) - functional magnetic resonance imaging , resting state fmri , neuroscience , stimulus (psychology) , brain mapping , blood oxygen level dependent , human brain , psychology , magnetic resonance imaging , brain activity and meditation , medicine , cognitive psychology , radiology , electroencephalography
Today, functional magnetic resonance imaging (fMRI) allows to plan surgery based on the topography of functionally important areas of the human brain cortex and tumor. This method can complement the surgical strategy with significant clinical information. The stimulus-dependent fMRI with motor and language paradigms is generally used for preoperative planning. The study outcome depends on the patient's ability to perform tasks paradigm, which is broken in brain tumors. In an attempt to overcome this problem, resting-state fMRI (rs-fMRI) is used for brain mapping. Rs-fMRI is based on the measurement of spontaneous fluctuations of the BOLD signal (blood oxygen level-dependent), representing the functional structure of the brain. In contrast to stimulus-dependent fMRI, rs-fMRI provides more complete information about functional architecture of the brain. rs-fMRI is used in conditions where the results of stimulusdependent fMRI may be falsely positive or in the absence of the possibility of its implementation. In aggregate, both methods significantly expand the efficiency and specificity of preoperative planning.