Open AccessANTIMICROBIAL ACTIVITY OF METHANOL EXTRACT FROM STEM BARK OF Cinnamomum sintoc
Author(s) -
Nurdin Saidi,
Hira Helwati,
Lailatul Qhadariah Lubis,
Muhammad Bahi
Publication year - 2017
Publication title -
jurnal natural/jurnal natural
Language(s) - English
Resource type - Journals
eISSN - 2541-4062
pISSN - 1411-8513
DOI - 10.24815/jn.v0i0.8049
Subject(s) - antimicrobial , candida albicans , antibacterial activity , staphylococcus aureus , maceration (sewage) , bark (sound) , agar dilution , traditional medicine , chemistry , methanol , microbiology and biotechnology , chromatography , bacteria , biology , minimum inhibitory concentration , medicine , organic chemistry , ecology , genetics , materials science , composite material
Antimicrobial activity of methanol extract from stem bark of Cinnamomum sintoc has been evaluated against Candida albicans, Staphylococcus aureus and Escherichia coli. The extraction of compound was carried out by maceration, then isolation by column chromatograph, which yielded five (5) subfractions (A-E). Activity against fungus C. albicans, S. aureus bacteria dan E. coli using agar dilution method in paper disk. Methanol extract was not potent against antifungal activity but shows antibacterial activity with medium category. Subfraction C showed that antibacterial activity against S. aureus and E. coli with weak category, but subfractions D and E did not show any activity.