Open AccessThe Diverse and Heterogeneous Clinical Features of Juvenile Psoriatic Arthritis
Author(s) -
С.Н. Чебышева,
Елена Жолобова,
N. A. Geppe,
K.V. Aleksanyan,
А.V. Meleshkina,
Khitrov Alexandr Nikolaevich,
Saltykov Alexandr Borisovich,
Tachieva Bella Isaevna,
Vorobyev Sergey Ivanovich,
Bolevich Stefani Sergeevna,
Bolevich Sergey Brankovich
Publication year - 2021
Publication title -
serbian journal of experimental and clinical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.131
H-Index - 8
eISSN - 2335-075X
pISSN - 1820-8665
DOI - 10.2478/sjecr-2021-0066
Subject(s) - medicine , psoriatic arthritis , psoriasis , polyarthritis , arthritis , dermatology , juvenile rheumatoid arthritis , disease
Juvenile Psoriatic Arthritis (JPsA) is a chronic inflammatory disorder that accounts for 3-10% of all juvenile arthritis. The main objective is to identify the clinical features of psoriatic arthritis in children. This study was open-label, single-center, prospective, observational (1989-2020) cohort clinical study included 85 patients (3-17.0 y/o) who met Vancouver and I/E criteria. The features of skin and articular syndromes in children with JPsA were revealed. In most patients with PSA, the disease began at the age of 6.6 years. In childhood, arthritis is usually preceded by psoriasis. The most common clinical form of psoriasis is plaque psoriasis. At the onset of the disease, symmetric polyarthritis predominates. During the disease, transformation of the joint syndrome with a predominance of rheumatoid arthritis is noted. All observed patients showed pronounced osteoporosis, which is not characteristic of JPsA.