Open AccessDiffuse Cutaneous Mastocytosis (Pigmented Maculopapular Cutaneous Mastocytosis) in a Cat
Author(s) -
M. Szczepanik,
Piotr Wilkołek,
Anna Śmiech,
Iwona Taszkun
Publication year - 2020
Publication title -
macedonian veterinary review/macedonian veterinary review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.178
H-Index - 6
eISSN - 1857-7415
pISSN - 1409-7621
DOI - 10.2478/macvetrev-2019-0025
Subject(s) - cutaneous mastocytosis , pathology , dermis , metachromasia , stain , medicine , urticaria pigmentosa , mast cell , systemic mastocytosis , staining , bone marrow , immunology
Diffuse cutaneous mastocytosis was diagnosed in a 6-year-old, indoor, neutered female domestic European shorthair cat. Marked pruritus located mainly on the head and neck was noticed in the cat and in this area the animal had developed alopecia, crusts, and plaques. Histologically, monomorphic mast cells were found in the superficial dermis and around the hair follicles. Mast cells were well differentiated, with central nuclei and granular cytoplasm, with metachromatic granules which stained positively with Toluidine blue stain. The animal was successfully treated with oclacitinib at a dose of 1 mg/kg, twice a day per os.