Open AccessClinical and Histopathological Findings of Chordomas: a Case Report
Author(s) -
Saime Sağıroğlu,
Sezen Koçarslan,
Selman Sarıca,
Nagihan Bilal
Publication year - 2018
Publication title -
folia medica/folia medica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.245
H-Index - 21
eISSN - 1314-2143
pISSN - 0204-8043
DOI - 10.2478/folmed-2018-0006
Subject(s) - clivus , skull , medicine , chordoma , notochord , distant metastasis , metastasis , radiation therapy , histopathological examination , axial skeleton , radiology , pathology , surgery , anatomy , cancer , biology , embryo , embryogenesis , microbiology and biotechnology
Chordomas are rare malignant tumors that develop from the residual of embryonic notochord. These tumors may be seen along the spine and have a local aggressive progression. Skull base chordomas often originate from the clivus as localization. These tumors are usually found to be overgrown when they are diagnosed. They are locally invasive and rarely develop distant metastasis. These chordomas cannot usually be completely removed due to their localization. Because these tumors are advanced at the time of diagnosis and are adjacent to important structures, they are among the tumors with high rates of mortality and morbidity. Surgery and/or radiotherapy is administered for the treatment.