Open AccessThe role of hydrogen sulfide in gastrointestinal tract functioning (review)
Author(s) -
Н. І. Волощук,
И. В. Таран,
О. S. Pashynska,
A.V. Melnyk,
Savva Magdebura
Publication year - 2020
Publication title -
current issues in pharmacy and medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.134
H-Index - 9
eISSN - 2300-6676
pISSN - 2084-980X
DOI - 10.2478/cipms-2020-0009
Subject(s) - gastrointestinal tract , medicine , hydrogen sulfide , medline , cochrane library , intensive care medicine , physiology , bioinformatics , meta analysis , biochemistry , biology , chemistry , sulfur , organic chemistry
Despite a fairly large amount of literature data about the involvement of hydrogen sulfide in physiological and pathophysiological processes, its role in gastrointestinal tract functioning has not been studied sufficiently. This review systematizes and generalizes the mechanisms of H 2 S-associated regulation of gastrointestinal secretion and motility on the basis of literature sources processing and own research results. We analysed world professional literature and sources in Google Scholar, PubMed, MedLine, Embase, Cochrane, and data from more than 50 articles and books on the problem were processed in the article. This review gives a synopsis of the H2S function in the regulation of the secretory and motor-evacuation function, and in stimulating the reparative properties of the digestive tract, and indicates the main mechanisms.