Open AccessMathematical analysis of a B-cell chronic lymphocytic leukemia model with immune response
Author(s) -
Youcef Belgaid,
Mohamed A. Helal,
Ezio Venturino
Publication year - 2019
Publication title -
applied mathematics and nonlinear sciences
Language(s) - English
Resource type - Journals
ISSN - 2444-8656
DOI - 10.2478/amns.2019.2.00052
Subject(s) - chronic lymphocytic leukemia , immune system , nonlinear system , ordinary differential equation , leukemia , mathematics , b cell , immunology , differential equation , biology , mathematical analysis , physics , antibody , quantum mechanics
A B-cell chronic lymphocytic leukemia has been modeled via a highly nonlinear system of ordinary differential equations. We consider the rather important theoretical question of the equilibria existence. Under suitable assumptions all model populations are shown to coexist.