Open AccessDistribution of Gadolinium-based Contrast Agent after Leaking into the Cerebrospinal Fluid: Comparison between the Cerebral Cisterns and the Lateral Ventricles
Author(s) -
Toshio Ohashi,
Shinji Naganawa,
Saeko Iwata,
Kayao Kuno
Publication year - 2021
Publication title -
magnetic resonance in medical sciences
Language(s) - English
Resource type - Journals
eISSN - 1880-2206
pISSN - 1347-3182
DOI - 10.2463/mrms.mp.2020-0016
Subject(s) - medicine , choroid plexus , cistern , cerebrospinal fluid , cerebral ventricle , gadolinium , lateral ventricles , subarachnoid space , ventricle , cisterna magna , radiology , pathology , nuclear medicine , anatomy , central nervous system , cardiology , materials science , archaeology , metallurgy , history
Leakage of a small amount of intravenously administered gadolinium-based contrast agents (GBCAs) into the cerebrospinal fluid (CSF) space has been reported, even in healthy subjects without blood-brain barrier disruption. Several candidates including the choroid plexus and cortical veins have been proposed as the source of the leakage. The purpose of this study was to evaluate the distribution of intravenously administered GBCA leakage into the CSF by comparing the contrast enhancement of the cerebral cisterns to the lateral ventricles (LVs).