Open AccessCoronavirus disease 2019 and cardiovascular implications
Author(s) -
Silvia Frattini,
Gloria Maccagni,
Leonardo Italia,
Marco Metra,
Gian Battista Danzi
Publication year - 2020
Publication title -
journal of cardiovascular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.458
H-Index - 47
eISSN - 1558-2035
pISSN - 1558-2027
DOI - 10.2459/jcm.0000000000001068
Subject(s) - medicine , disease , covid-19 , intensive care medicine , coronavirus , angiotensin converting enzyme 2 , peptidyl dipeptidase a , cardiovascular health , angiotensin converting enzyme , cardiology , blood pressure , infectious disease (medical specialty)
: The coronavirus disease 2019 (COVID-19) has important implications for the cardiovascular care of patients. COVID-19 interacts with the cardiovascular system on multiple levels, increasing morbidity in patients with underlying cardiovascular conditions and favoring acute myocardial injury and dysfunction. COVID-19 infection may also have long-term implications for overall cardiovascular health. Many issues regarding the involvement of the cardiovascular system remain controversial. Despite angiotensin-converting enzyme 2 serving as the site of entry of the virus into the cells, the role of angiotensin-converting enzyme inhibitors or AT1 blockers requires further investigation. Therapies under investigation for COVID-19 may have cardiovascular side effects. Treatment of COVID-19, especially the use of antivirals, must be closely monitored. This article is a review of the most updated literature.