The pemphigus monoclonal antibody clone P5G6 (AX353) retains cell-surface staining by immunofluorescence and desmoglein binding by ELISA in an engineered scFv-Fc format | Zendy

Christoph M. Hammers | Zendy; Jens Wrammert | Zendy

Open Access

The pemphigus monoclonal antibody clone P5G6 (AX353) retains cell-surface staining by immunofluorescence and desmoglein binding by ELISA in an engineered scFv-Fc format

Author(s) -

Christoph M. Hammers,

Jens Wrammert

Publication year - 2022

Publication title -

antibody reports

Language(s) - English

Resource type - Journals

ISSN - 2624-8557

DOI - 10.24450/journals/abrep.2022.e756

Subject(s) - immunofluorescence , recombinant dna , desmoglein 1 , clone (java method) , monoclonal antibody , microbiology and biotechnology , antibody , desmoglein , desmoglein 3 , surface protein , chemistry , biology , virology , autoantibody , immunology , gene , biochemistry

The recombinant human antibody clone P5G6 (AX353) in an engineered scFv-Fc format detects by immunofluorescence cell-surface proteins on cryosections of monkey esophagus. The same antibody detects by ELISA recombinant human desmoglein 3 and desmoglein 1 protein.

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