Open AccessThe pemphigus monoclonal antibody clone P5G6 (AX353) retains cell-surface staining by immunofluorescence and desmoglein binding by ELISA in an engineered scFv-Fc format
Author(s) -
Christoph M. Hammers,
Jens Wrammert
Publication year - 2022
Publication title -
antibody reports
Language(s) - English
Resource type - Journals
ISSN - 2624-8557
DOI - 10.24450/journals/abrep.2022.e756
Subject(s) - immunofluorescence , recombinant dna , desmoglein 1 , clone (java method) , monoclonal antibody , microbiology and biotechnology , antibody , desmoglein , desmoglein 3 , surface protein , chemistry , biology , virology , autoantibody , immunology , gene , biochemistry
The recombinant human antibody clone P5G6 (AX353) in an engineered scFv-Fc format detects by immunofluorescence cell-surface proteins on cryosections of monkey esophagus. The same antibody detects by ELISA recombinant human desmoglein 3 and desmoglein 1 protein.