Open AccessThe Role of IL-6 in Inflammatory Reaction during Coronavirus-19 Infection: A Review
Author(s) -
Aesha S. Ali
Publication year - 2022
Publication title -
journal of communicable diseases/journal of communicable diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.151
H-Index - 26
eISSN - 2581-351X
pISSN - 0019-5138
DOI - 10.24321/0019.5138.202233
Subject(s) - cytokine , immunology , myokine , inflammation , interleukin 6 , medicine , coronavirus , interleukin , disease , inflammatory response , covid-19 , proinflammatory cytokine , infectious disease (medical specialty) , pathology , skeletal muscle
Interleukin 6 (IL-6) is an interleukin that works as a pro-inflammatory cytokine and as an anti-inflammatory myokine. The production of IL-6 in humans is under genetic control. IL-6 is a pleiotropic cytokine created in response to tissue injury and infections. IL-6 is one of the basic cytokines after stimulated macrophages. Hence, control of systemic IL-6 levels in SARS-CoV-2 infected patients may be a consideration for COVID-19 disease. This review will focus on the role of IL-6 in diagnosis and follow up of infection in addition to being the target for treatment.