Open AccessThe Study of Biochemical Markers in Chronic Renal Failure Patients in Pre- and Post-Haemodialysis
Author(s) -
Mohammed Abed Jawad,
Abed J. Kadhim
Publication year - 2021
Publication title -
journal of communicable diseases/journal of communicable diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.151
H-Index - 26
eISSN - 2581-351X
pISSN - 0019-5138
DOI - 10.24321/0019.5138.202166
Subject(s) - creatinine , medicine , malondialdehyde , diabetes mellitus , chronic renal failure , lipid peroxidation , gastroenterology , renal function , kidney disease , endocrinology , oxidative stress
Background: The current research is designed to investigate alterations in lipid peroxidation (malondialdehyde - MDA) and renal markers (urea and creatinine) in patients of chronic renal failure (CRF) as compared to the control group. Method: The study included 55 subjects, who were separated into two groups: control group, which included 15 healthy members with no history of systematic illness; and patients group, which included 40 patients with CRF divided into four groups “Non: CRF patients without any accompanied disease, DM: CRF patients with diabetes mellitus, HT: CRF patients with hypertension, and HT + DM: CRF patients with diabetes mellitus and hypertension”. Results: The findings reveal that there is a notable increase in serum concentration of MDA, urea, and creatinine, in patients group as compared to the control group. Conclusion: In all chronic renal failure patients with or without any accompanying disease, lipid peroxidation is present in pre- and post-haemodialysis patients as well as patients with CRF have high levels of urea and creatinine compared with healthy groups.