Open AccessDETEKSI ANTI GLUTAMIC ACID DECARBOXILASE/TYROSINE PHOSPHATASE (ANTI GAD/IA2) PADA PENDERITA DM TIPE 1 ANAK
Author(s) -
Puspa Wardhani,
Siswanto Darmadi,
Muhammad Faizi,
Netty Harjantien
Publication year - 2018
Publication title -
indonesian journal of clinical pathology and medical laboratory
Language(s) - English
Resource type - Journals
ISSN - 2477-4685
DOI - 10.24293/ijcpml.v14i2.907
Subject(s) - medicine , glutamate decarboxylase , gastroenterology , enzyme , biochemistry , chemistry
Our study evaluated anti GAD/IA2 levels in Type 1 DM patients in Dr. Soetomo Hospital Surabaya. We conducted cross sectionalstudy, involving Type 1 DM patients that already been established (C-Peptide bellow normal). Patient’s age range was from 2.8 yearsold to 17 years old, so they were regarded as children. We used anti GAD/IA2 reagents from Euroimmun wich had basic principal EIA.Twelve patients was involved in this study. The average level of anti GAD/IA2 was 210.37 IU/mL. The Average level of anti GAD/IA2was higher in female than male patients (227.38 IU/mL dan 162 IU/mL). All patients had anti GAD/IA2. This examination can beusefull for screenimg one who has high risk in developing type 1A DM, especially first degree relatives.