Open AccessSkin damage after the hematopoietic stem cell transplantation. Literature review
Author(s) -
Т. З. Алиев,
Е. Б. Мачнева,
Н. В. Сидорова,
Т. С. Белышева,
Т. Т. Валиев,
К. И. Киргизов
Publication year - 2020
Publication title -
voprosy gematologii/onkologii i immunopatologii v pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 3
eISSN - 2414-9314
pISSN - 1726-1708
DOI - 10.24287/1726-1708-2020-19-2-184-192
Subject(s) - etiology , hematopoietic stem cell transplantation , medicine , disease , pathogenesis , dermatology , stem cell , transplantation , graft versus host disease , haematopoiesis , intensive care medicine , immunology , surgery , pathology , biology , genetics
Skin damage after hematopoietic stem cell transplantation (HSCT) is common and important diagnostic and therapeutic problem. The most significant causes of skin lesions in HSCT are drug toxicity, infections, and manifestations of skin acute and chronic “graft versus host” disease. Each of the complications can manifest in various forms, as well as to combine with others, exerting a significant negative effect on the patient’s condition, in severe cases posing a threat to the patient’s life. The article summarizes data on the etiology, features of pathogenesis, clinical forms, the main methods of diagnosis and therapy of the most common skin complications of HSCT.