Open AccessLeptomeningeal canceromatosis in patient with parameningeal rhabdomyosarcoma
Author(s) -
Л. Л. Казакова,
Н. В. Жуков
Publication year - 2019
Publication title -
voprosy gematologii/onkologii i immunopatologii v pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 3
eISSN - 2414-9314
pISSN - 1726-1708
DOI - 10.24287/1726-1708-2019-18-4-90-98
Subject(s) - pathognomonic , rhabdomyosarcoma , medicine , radiology , medical physics , pathology , disease , sarcoma
The development of leptomeningeal carcinomatosis (LC) is quite a frequent event during a rhabdomyosarcoma with parameningeal localization, usually known as a parameningeal rhabdomyosarcoma (PM RMS). However, the diagnosis and treatment of this kind of progression are still difficult for pediatricians and pediatric oncologists due to the small absolute number of PM RMS patients, which makes it impossible to accumulate sufficient clinical experience, as well as due to the absence of a pathognomonic clinical picture and a standardized specific therapy. The article describes 3 clinical cases of LC during PM RMS and provides an overview of existing literature focusing on this problem. Parents patients agreed to use personal data in research and publications.