Open AccessPediculicidal Activity of Cem-ceman White Cempaka Flower (Michelia alba DC.) against Pediculus humanus capitis
Author(s) -
Ahmad Fadli Robby,
Iman Surya Pratama,
Galuh Tresnani
Publication year - 2021
Publication title -
ad-dawaa' journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 2654-6973
pISSN - 2654-7392
DOI - 10.24252/djps.v4i1.21154
Subject(s) - traditional medicine , horticulture , biology , permethrin , botany , toxicology , medicine , pesticide , agronomy
The prevalence of pediculosis reported in Asia has ranged from 0.7% to 59%. High resistance and side effects is a challenge in using the pediculicidal agents. The widely use and empirical as well as scientific studies of traditional plants for anti-lice were already done, one of them is cempaka. The aim of this study was to determine the pediculicidal activity of cem-ceman white cempaka flower (Michelia alba DC.) on Pediculus humanus capitis in vitro. The white cempaka flowers made into cem-ceman preparations by mixing and soaking in coconut oil until 3 days. Pediculisidal activity was tested by filter paper diffusion test method with 3 replications. Data were analyzed using Kruskal-Wallis followed by post hoc Mann-Whitney Method test with software SPSS v.16. The phytochemical screening showed that sample contains alkaloid, tannin, saponin, and triterpenoid. Pediculidal activity test showed that cem-ceman white cempaka flower has pediculicidal effect in 10% concentration (w/v) with 66.67% mortality and 15% concentration (w/v) with 77.33% mortality. In conclusion cem-ceman white cempaka flowers has pediculicidal activity at concentration 10% and 15% but lower than permethrin 1% (p<0.05).