Open AccessPersistence of Cypermethrin and Permethrin and their Effects on Rat Blood Hematological Characteristics
Author(s) -
Ayman H. Mansee
Publication year - 1998
Publication title -
journal of agricultural and marine sciences
Language(s) - English
Resource type - Journals
eISSN - 2410-1079
pISSN - 2410-1060
DOI - 10.24200/jams.vol3iss1pp35-39
Subject(s) - permethrin , cypermethrin , pyrethroid , white blood cell , red blood cell , zoology , biology , persistence (discontinuity) , physiology , immunology , pesticide , agronomy , geotechnical engineering , engineering
Persistence and biochemical characteristics of cypertnethrin and permethrin in the blood of male rats were studied following oral administration of a single dose containing 10 mg.kg -1 of body weight of each pyrethroid. The highest residue concentrations of cypermethrin (2.38 ug.ml-1) and permethrin (8.83 ug.ml-1) in rat blood tissue were detected 24 h after treatment. After two weeks cypermethrin residues decreased to 0.013 ug.ml -1 , whereas permethrin was not detected. Both pyrcthroids decreased the red blood cell (RBC) count, and packed cell volume (PCV) The greatest reduction in RBC count and PCV occurred at 504 h and 336 h respectively. Moreover, the result of post treatment white blood cell (WBC) count was influenced more by permethrin than by cypermethrin, especially after 80 h, 168 h and 504 h of treatment. However, the blood haemoglobin concentration in treated rats was not affected by either pyrethroid.