Open AccessEFFECTS OF PROBIOTICS CONSUMPTION AND RESISTANCE EXERCISE ON BONE METABOLISM MARKERS IN PHYSICALLY INACTIVE YOUNG MALES
Author(s) -
Nur Syazwani Ibrahim,
Ayu Suzailiana Muhamad,
Chee Keong Chen,
Foong Kiew Ooi
Publication year - 2022
Publication title -
malaysian journal of sport science and recreation
Language(s) - English
Resource type - Journals
eISSN - 2735-1238
pISSN - 1823-3198
DOI - 10.24191/mjssr.v18i1.17643
Subject(s) - bone remodeling , osteocalcin , parathyroid hormone , medicine , endocrinology , bone resorption , resistance training , placebo , n terminal telopeptide , alkaline phosphatase , chemistry , calcium , biochemistry , pathology , alternative medicine , enzyme
This study aims to investigate the effects of probiotics supplementation and resistance exercise on bone metabolism markers and parathyroid hormones in physically inactive young men. Fourty-one healthy participants completed the study. They were randomized into sedentary placebo control (C: n=10), probiotics (P: n=10), resistance exercise with placebo (E: n=12), and probiotics consumption with resistance exercise (PE: n=9) groups. Participants in the P and PE consumed multi-strain probiotics containing 3x1010 CFU of L. acidophilus BCMC® 12130, L. casei BCMC® 12313, L. lactis BCMC® 12451, B. bifidum BCMC® 02290, B. infantis BCMC® 02129 and B. longum BCMC® 02120 twice daily for 12 weeks. Participants in the E and PbE performed circuit training comprised of 10 resistance exercises 3 times/week. Body height and weight, blood pressure, resting heart rate and blood samples were collected at pre and post-tests. Blood samples were analysed for the concentration of bone formation markers [alkaline phosphatase (ALP) and osteocalcin (OC)], bone resorption marker [cross-linked carboxyterminal telopeptide of type 1 collagen (1CTP)] and parathyroid hormones (PTH). There were no significant differences (p>0.05) in all measured parameters between groups and within each group (p>0.05). Nevertheless, ALP and OC concentration exhibited increasing trends in PE group. There was a decreasing trend in PTH concentration in P and PE groups. As a conclusion, probiotics consumption with resistance exercise resulted in increased trends of bone formation markers and a small reduction in the bone resorption marker implying that this combination may elicit beneficial effects in improving bone formation in young physically inactive males.