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A Malignant Lymphoma Presenting as a Non-healing Oral Ulcer
Author(s) -
Ahmad Izani Mohd Safian,
Irfan Mohamad,
Azliana Aziz,
Faezahtul Arbaeyah Hussain,
Azlan Husin,
Sarah Zulkarnain
Publication year - 2022
Publication title -
journal of clinical and health sciences
Language(s) - English
Resource type - Journals
ISSN - 0127-984X
DOI - 10.24191/jchs.v7i1.11279
Subject(s) - medicine , lymphoma , lesion , pyogenic granuloma , oral cavity , oral mucosa , pathology , disease , dermatology , dentistry
Lymphomas are the second most common non-epithelial malignant tumour in the oral and maxillofacial region. Non-Hodgkin lymphoma (NHL) is more frequently diagnosed eventhough oral cavity involvement is less than 4% of all NHLs. Usually, the oral manifestation of NHL is secondary to the widespread involvement. Primary oral NHL is relatively rare and difficult to diagnose in clinical setting as it presents as local swelling, pain, discomfort and mimics pyogenic granuloma, periodontal disease, osteomyelitis and other malignancies. A chronic, solitary non-healing ulcerative lesion of the oral mucosa is often misdiagnosed as non-neoplastic especially in a previously healthy young adult. Here, we share a case of extranodal diffuse large B-cell lymphoma of the soft palate, in a 22-year-old healthy gentleman with no other symptoms. Meticulous clinical evaluation and complete investigations are required for prompt diagnosis, timely treatment which carries betterprognosis.

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