Open AccessBehavioral therapy and pharmacotherapy for relapse prevention in abstinent smokers: a rapid review and meta-analysis for the Korea Preventive Service Task Force
Author(s) -
Naae Lee,
Eon Sook Lee,
Jae Moon Yun,
Cheol Min Lee,
Seung Won Oh,
Younglee Choi,
Belong Cho
Publication year - 2021
Publication title -
osong public health and research perspectives
Language(s) - English
Resource type - Journals
eISSN - 2233-6052
pISSN - 2210-9099
DOI - 10.24171/j.phrp.2021.0017
Subject(s) - medicine , meta analysis , pharmacotherapy , smoking cessation , abstinence , psychological intervention , randomized controlled trial , relapse prevention , medline , cinahl , relative risk , confidence interval , physical therapy , psychiatry , pathology , political science , law
ObjectivesThis study aimed to assess the effectiveness of relapse prevention interventions involving behavioral and pharmacological treatment among abstinent smokers.MethodsThis rapid review was conducted using MEDLINE, Cochrane CENTRAL, CINAHL, Embase, KMbase, and KoreaMed to identify studies published until June 20, 2020. The participants were abstinent smokers who quit smoking on their own, due to pregnancy, hospitalization, or by participating in a smoking cessation program. We found a systematic review that fit the objective of this study and included 81 randomized controlled trials (RCTs). Studies that did not present information on smoking cessation status, had no control group, or used reward-based interventions were excluded. Random effect and fixed effect meta-analyses were used to estimate the relative risk (RR) and 95% confidence interval (CI). In subgroup analyses, differences between subgroups were verified based on the participant setting, characteristics, intervention type, and intensity.ResultsFollowing screening, 44 RCTs were included in the meta-analysis. The review reported no differences in the success rate of relapse prevention between the behavioral interventions. Pharmacotherapy interventions showed higher success rates (RR, 1.15; 95% CI, 1.05−1.26; I 2 =40.71%), depending on prior abstinence duration and the drug type. Conclusions: The results indicated that pharmacotherapy has a significant effect on preventing relapse among abstinent smokers.