Open AccessValidity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
Author(s) -
Juyoung Kim,
MinWoo Jo,
Hyeon-Jeong Lee,
Sei-Hyun Ahn,
Byung Ho Son,
Jong Won Lee,
Sae Byul Lee
Publication year - 2021
Publication title -
osong public health and research perspectives
Language(s) - English
Resource type - Journals
eISSN - 2233-6052
pISSN - 2210-9099
DOI - 10.24171/j.phrp.2021.0005
Subject(s) - intraclass correlation , medicine , breast cancer , kappa , quality of life (healthcare) , confidence interval , convergent validity , reliability (semiconductor) , visual analogue scale , cohen's kappa , correlation , criterion validity , cancer , physical therapy , psychometrics , statistics , clinical psychology , construct validity , mathematics , power (physics) , physics , geometry , nursing , quantum mechanics , internal consistency
Objectives: This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea.Methods: The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC).Results: The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780).Conclusion: The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.