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Optimization of methodology for the extraction of polyphenolic compounds with antioxidant potential and α-glucosidase inhibitory activity from Jamun (Syzygium cumini L.) seeds
Author(s) -
M. Arivalagan,
D R Priyanka,
A. Rekha
Publication year - 2021
Publication title -
journal of horticultural sciences/journal of horticultural sciences (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.101
H-Index - 1
eISSN - 2582-4899
pISSN - 0973-354X
DOI - 10.24154/jhs.2021.v16i01.003
Subject(s) - chemistry , polyphenol , acetone , flavonoid , extraction (chemistry) , antioxidant , syzygium , aqueous solution , solvent , chromatography , food science , organic chemistry , botany , biology
Jamun (Syzygium cumini L.) seed is one of the rich sources of polyphenolic compounds​ ​with antioxidant potential and α-glucosidase inhibitory activity. A study was conducted to​ ​optimize the methodology for the extraction of polyphenolic compounds (total phenolic​ ​and flavonoid contents) with antioxidant potential and α-glucosidase inhibitory activity​ ​from Jamun seed powder. The study showed that the nature of solvent and extraction​ ​conditions had a significant effect on total phenolic content (TPC), total flavonoid content​ ​(TFC), antioxidant potential, and α-glucosidase inhibitory activity. The TPC varied between​ ​6.0 (mg/g Jamun seed powder) for the acetone extract to 119.2 (mg/g) for 80% aqueous​ ​acetone extract and TFC varied between 1.06 mg/g for the acetone to 10.81 mg/g for the​ ​80% aqueous methanol. From the study, it was apparent that an aqueous form of acetone​ ​(acetone: water 80:20, v/v) is a better solvent system for extraction of polyphenolic​ ​compounds with high antioxidant potential and α-glucosidase inhibitory activity.​ ​Ultrasonication for 60 min increased the efficiency of phenolic extraction.

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