Open AccessEvaluation of Some Biochemical Markers in Patient's with Polycystic Ovarian Syndrome
Author(s) -
Farah T. O. Al-Jumaili,
Aqeel Jafar Naji,
Thamer Mutlag Jasim
Publication year - 2015
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2015.9.2.433
Subject(s) - body mass index , medicine , endocrinology , obesity , triglyceride , insulin , waist–hip ratio , waist , insulin resistance , cholesterol
The present study aims to detect several biochemical markers associated with PCOS (Polycysticovary syndrome) in Iraqi women comparing the results with control normal fertile women andalso studying the effect of obesity on the same biochemical markers. Ninety eight women withPCOS, 51 non-obese [body mass index (BMI) less than 25 kg/m2] and 47 obese (BMI >25 kg/m2)were enrolled for the study. Each group of them was compared forty normal fertile women ascontrol group matched for each in age and BMI. The first part of this study was devoted to themeasurement of Body Mass Index (BMI) and Waist Hip Ratio (WHR), subdivided PCOSaccording to the body mass index, and measurement of fasting insulin, fasting glucose,Homeostatic Model Assessment (HOMA), HbA1c and lipid profile. A significant differences wasfound in HbA1c (P≤0.0001) VLDL (p≤0.0001), triglyceride (p≤0.05) and cholesterol (p≤0.05)between obeses and lean PCOS patients. Insulin serum level (P≤0.0001) was highly significantlyincreased in obeses PCOS patients as compared to obeses control, the serum insulin (P≤0.0001)also significantly increased in lean PCOS women when compared with lean control. There was asignificant differences between HOMA (P≤0.05) in obeses PCOS patients than in the obesecontrol group and between obese and lean women PCOS patients.