Open AccessEffect of different doses of uranyl acetate on some blood parameters and hepatic enzymesin females rats.
Author(s) -
Sarah Ghazi Alzorii
Publication year - 2014
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2014.8.3.354
Subject(s) - medicine , distilled water , lactation , chemistry , zoology , endocrinology , oral administration , uranyl , pregnancy , biology , ion , organic chemistry , chromatography , genetics
This study was carried out to investigate effects of oral administration of uranyl acetate on haematological parameters and liver enzyme. For this purpose, twenty females mature Albino rats were divided into four equal groups, control group G1 administrated distilled water, the other three groups administrated orally 50,75,100 mg/kg/b.w. /day of uranyl acetate. The route of administration was oral intubations for 10 weeks, for 14 days before mating with untreated males, as well as during pregnancy 3 weeks and lactation 5 weeks. At the end of the treatment blood samples were collected from mothers of rats. The results were obtained a significant P 0.05 in G2 in the lymphocytes and monocytes percentage compared with control. And the results show significant P 0.05 in G2 in HB value compared with control. A significant P 0.05 in GOT and GPT in groups G2 and G3 and significant P 0.05 in CPK activity in groups G2,G3,G4 compared with control.