Open AccessCytotoxic effects of Ammi visnaga volatile oil on some cancer cell lines
Author(s) -
Zainab Y. Mohammed,
Saad M. Nada,
Mohammed M. F. Al-Halbosiy,
Shaimaa Y. Abdulfattah,
Baraa Abdulhadi Abdulhameed
Publication year - 2014
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2014.8.1.288
Subject(s) - cell culture , cytotoxic t cell , essential oil , cancer cell lines , chemistry , ammi , pharmacology , biology , cancer , chromatography , cancer cell , biochemistry , gene , in vitro , genetics , gene–environment interaction , genotype
Ammi visnaga a herbal plant is rich with important active constituents that make the plant to be described in traditional medicine and among them is the volatile oil. The oil extracted by distillation and then study it's cytotoxic effect on two cell line: The human pelvic rhanbdomyosarcoma (RD) and The mouse cell line( L20B) which expresses the genes for human cellular receptor for Polio viruses. Results showed that there were potent toxic effects on both cell lines RD&L20B specially at the concentration (100,50 and 25)µl/ml of the essential oil ,then decreased as the oil concentrations decreased.