The Effect of Crude Alcoholic Extract of Fenugreek Seeds Trigonella foenum on Prolactin and Luteinizing hormone in Male Rabbits

This study was designed to investigate the effect of crud alcoholic extract of fenugreek seeds (Trigonella foenum-graecum) on the levels of Prolactin and Leutinizing hormones in male rabbits. Forty eight male rabbits were used in this study. The animals were divided into four main groups; the first group received 1ml of DW (control), while the other three groups received )25, 50,75( mg /kg /day. These main groups were subdivided into three sub groups, according to the period of treatment (15, 30, 45) day, and they were labeled A, B, C, respectively. Blood samples were collected every 15 day for hormonal investigation. Treating with crud alcoholic extract of fenugreek seeds, leads to significant (P<0.05) increase in the mean of body and liver weight, in all groups (25, 50, 75) mg/ml and during all treating periods (15, 30, 45) day. The result showed no significant changes in the mean weight of kidney, in all main groups treated for 15 and 30 days, while groups treated with 50 and 75 mg/ml for 45 days, showed significant (P<0.05) increase. No significant changes were observed in the levels of Prolactin in all treated animals for 15 days, but significant (P<0.05) increase were observed in groups received 75 mg/ml for 30 days, and 50, 75 mg/ml treated for 45 days. Leutinizing hormone also didn’t show any significant changes, in all groups treated for 15 days, while significant (P<0.05) decrease was observed in all animals treated for 30 and 45 days. We can conclude from these result, that the crud alcoholic extract of fenugreek seeds, caused an increase in the mean of body, and Prolactin levels, but caused decreased in the levels of Leutinizing hormone.