Open AccessCytogenetic study of the pure Resveratrol extracted from grape skin on normal peripheral human blood lymphocytes
Author(s) -
Zainab Y. Mohammed,
Essam F. Al-Jumaily,
Nahi Y. Yaseen
Publication year - 2011
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2011.5.2.156
Subject(s) - resveratrol , polyphenol , mitosis , peripheral blood , human blood , human skin , mutagen , biology , pharmacology , traditional medicine , genotoxicity , cell , biochemistry , chemistry , microbiology and biotechnology , dna , immunology , genetics , medicine , toxicity , physiology , antioxidant , organic chemistry
his study was conducted with the aim to extract and purify a polyphenolic compound “Resveratrol” from black grapes skin Vitis vinifera cultivated in Iraq. The pure extracted resveratrol has been employed for a cytogenetic evaluation on the normal human blood lymphocytes and revealed that the substance reduced significantly the mitotic action of the mutagen (PHA). The results of the cytogenetic study suggested that the substance appeared to have potent antimitotic and antiblastic cell formation.