Cytogenetic study of the pure Resveratrol extracted from grape skin on normal peripheral human blood lymphocytes | Zendy

Zainab Y. Mohammed | Zendy; Essam F. Al-Jumaily | Zendy; Nahi Y. Yaseen | Zendy

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Cytogenetic study of the pure Resveratrol extracted from grape skin on normal peripheral human blood lymphocytes

Author(s) -

Zainab Y. Mohammed,

Essam F. Al-Jumaily,

Nahi Y. Yaseen

Publication year - 2011

Publication title -

journal of biotechnology research center

Language(s) - English

Resource type - Journals

eISSN - 2708-1370

pISSN - 1815-1140

DOI - 10.24126/jobrc.2011.5.2.156

Subject(s) - resveratrol , polyphenol , mitosis , peripheral blood , human blood , human skin , mutagen , biology , pharmacology , traditional medicine , genotoxicity , cell , biochemistry , chemistry , microbiology and biotechnology , dna , immunology , genetics , medicine , toxicity , physiology , antioxidant , organic chemistry

his study was conducted with the aim to extract and purify a polyphenolic compound “Resveratrol” from black grapes skin Vitis vinifera cultivated in Iraq. The pure extracted resveratrol has been employed for a cytogenetic evaluation on the normal human blood lymphocytes and revealed that the substance reduced significantly the mitotic action of the mutagen (PHA). The results of the cytogenetic study suggested that the substance appeared to have potent antimitotic and antiblastic cell formation.

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