Open AccessCytotoxic effect of the aqueous extract of Portulaca Oleracea L. on some cell lines
Author(s) -
Maeda H. Mohammad,
Zaynab S. Abdul-Gany,
Aymen A. Hassan
Publication year - 2011
Publication title -
journal of biotechnology research center
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2011.5.1.136
Subject(s) - portulaca , cytotoxic t cell , cell culture , in vitro , embryo , aqueous extract , chemistry , cell , apoptosis , biology , pharmacology , traditional medicine , biochemistry , medicine , botany , microbiology and biotechnology , genetics
he cytotoxic effect of the aqueous extract of Portulaca oleracea L. was tested in vitro against the cancer cell AMN3 (Murine Mammary Adenocarcinoma cell line) and the normal cell REF (Rat Embryo Fibroblasts). Proliferation was significantly reduced at high concentrations (300-1000 µg/ml) during the first 24 hrs. of contact on AMN3. while the extract showed no significant effect during different period time of exposure as compared with control against REF cells.
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