Open AccessEffect of sage (Salvia officinalis) aqueous extract on mitotic index in albino male mice
Author(s) -
M. Al-Ezzy Roqaya,
Khulood Al-Samarrae,
Ali H. Ad'haih
Publication year - 2010
Publication title -
maǧallaẗ markaz buḥūṯ al-taqniyyaẗ al-aḥyāʾiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2708-1370
pISSN - 1815-1140
DOI - 10.24126/jobrc.2010.4.1.91
Subject(s) - sage , salvia officinalis , mitotic index , bone marrow , aqueous extract , pharmacology , traditional medicine , mitosis , salvia , biology , officinalis , medicine , immunology , microbiology and biotechnology , physics , nuclear physics
This study aimed to evaluate the effect of aqueous extract of sage (Salvia officinalis) on bone marrow cells in albino male mice by using three doses ( 83.9, 167.8 or 251.7 mg/kg) and cytosar drug at dose of ( 1.54 mg/kg). The results showed that sage has the ability to increase the mitotic index in mice in comparing with the negative control and in mice treated with cytosar drug that caused reduction in mitotic index. The results of pre- and post-treatment with the ideal dose of aqueous extract of sage and cytosar drug showed the ability of sage to increase the mitotic index of bone marrow cells in mice in comparing with the negative controls.