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Ototoksisitas Aminoglikosida
Author(s) -
Fransiska Fransiska
Publication year - 2019
Publication title -
keluwih
Language(s) - English
Resource type - Journals
ISSN - 2715-6419
DOI - 10.24123/kesdok.v1i1.2495
Subject(s) - medicine , ototoxicity , anamnesis , gynecology , pharmacology , chemotherapy , cisplatin
— Aminoglicoside are categorized as cochleotoxic and vestibulotoxic drugs that can cause patients to experience hearing loss or vertigo, depends on what type of aminoglicoside consumed. This paper discuss type, pharmaceutical preparation, pharmacokinetics, work mechanism and clinical use of aminoglycoside. How to diagnose, treatment, and also how to prevent aminoglicoside ototoxicity are also explained further in this paper. Abstrak— Golongan obat aminoglikosida mampu menyebabkan kokleotoksik, maupun vestibulotoksik sehingga penderita mengalami penurunan pendengaran atau vertigo. Hal tersebut tergantung dari jenis aminoglikosida yang dikonsumsi. Tulisan ini membahas berbagai jenis aminoglikosida, sediaan, farmakokinetik, mekanisme kerja, dan penggunaannya secara klinis. Diagnosis yang  meliputi anamnesis, pemeriksaan fisik, pemeriksaan penunjang, terapi, dan pencegahan ototoksisitas yang disebabkan oleh aminoglikosida turut dipaparkan lengkap.

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