Open AccessMODERN APPROACH AND CLINICAL EXPERIENCE OF DIAGNOSIS OF CONGENITAL TOXOPLASMOSIS
Author(s) -
Tetyana Znamenska,
О. В. Воробйова,
O. Bakaeva,
S. Starenka,
Kateryna Fedchuk,
Т. Holota,
V. Saminina
Publication year - 2021
Publication title -
neonatologìâ, hìrurgìâ ta perinatalʹna medicina
Language(s) - English
Resource type - Journals
eISSN - 2413-4260
pISSN - 2226-1230
DOI - 10.24061/2413-4260.xi.4.42.2021.13
Subject(s) - toxoplasmosis , congenital toxoplasmosis , medicine , disease , miscarriage , seroconversion , pediatrics , pregnancy , serology , infectious disease (medical specialty) , prenatal diagnosis , spiramycin , fetus , obstetrics , intensive care medicine , toxoplasma gondii , immunology , pathology , antibody , antibiotics , erythromycin , biology , microbiology and biotechnology , genetics
Diagnosis of congenital toxoplasmosis is one of the most pressing and complex problems of perinatology. Difficulties in the interpretation of serological tests, the lack of clearly defined steps in the detection of seroconversion in women leads to late diagnosis and the development of irreversible changes and severe complications from the newborn. When infected during pregnancy, the disease is extremely unfavorable for the fetus and can lead to miscarriage, stillbirth, intrauterine growth retardation or the formation of birth defects. This article presents a review of the literature on the modern diagnosis of congenital toxoplasmosis and presents his own clinical case of diagnostic search for this infectious disease in the newborn. Practitioners should keep in mind prenatal ultrasound markers, the main manifestations of the disease and methods of diagnosis, because timely recognized and confirmed congenital toxoplasmosis will have the best long-term treatment results and prognosis in the newborn.