Open AccessPlasma proteolytic and fibrinolytic activity in non-alcoholic steatohepatitis, combined with chronic obstructive pulmonary disease
Author(s) -
T. P. Tsyntar
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.4.72.2014.221
Subject(s) - fibrinolysis , medicine , pulmonary disease , alcoholic liver disease , steatohepatitis , gastroenterology , chronic liver disease , proteolysis , disease , pathology , fatty liver , cirrhosis , chemistry , enzyme , biochemistry
The study involved 30 patients with NASH, 30 patients with chronic obstructive pulmonary disease and 30 patients with non-alcoholic steatohepatitis in combination with chronic obstructive pulmonary disease. A substantial enhancement of proteolysis low and high molecular weight proteins, of colagenolytic activity of plasma and nonenzymatic fibrinolysis against reduction of content of α2-macroglobulin in serum and more pronounced decrease in activity of the enzymatic fibrinolysis in this combined pathology.