Open AccessIndicators of the bronchial lability and hyperreactivity in children with bronchial asthma and exercise induced bronchoconstriction
Author(s) -
О.К. Колоскова,
O. O. Shahova,
N. K. Bogutska
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.4.72.2014.194
Subject(s) - bronchoconstriction , asthma , bronchospasm , medicine , histamine , lability , bronchial hyperreactivity , bronchial spasm , immunology , respiratory disease , lung , chemistry , biochemistry
The results of the analysis of the bronchial hyperreactivity indicators in 60 children suffering from asthma with exercise induced bronchoconstriction and without exercise induced bronchospasm are presented in the article. It has been established that higher bronchial lability was typical for children with asthma and exercise induced bronchoconstriction. The bronchial hypersensitivity to inhaled histamine in a concentration less than 0,4 mg/ml with 77 % specificity, 71 % post-test probability and significant odds ratio indicate a phenotype of childhood asthma with exercise induced bronchoconstriction.