Open AccessThe affected and contralateral kidney morphological changes in course of one-sided rat pyelonephiritis model
Author(s) -
О. С. Федорук,
Olena Tiulienieva,
М. С. Степанченко
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.3.71.2014.158
Subject(s) - kidney , inflammation , medicine , urinary system , kidney disease , pathology , physiology
The research aimed to identify presence and severity of contralateral kidney tissue changes while opposite kidney inflammation progresses. Our own model was used for disease evoking in rats. The observation period lasted 10 days. Starting from the 3rd day, signs of hematogenous dissemination of infection/inflammation into contralateral kidney were registered. Starting from the 5th day urinogenous dissemination process was observed. By the 3rd day of study a cortical hyperemia in contralateral kidney was seen, which possibly was of compensatory origin. Based on research results, a primarily bilateral urinary tract inflammation/infection can be suspected.