Open AccessTreatment efficiency of subclinical atherosclerosis according to ultrasound scan of the heart and vessels and to the stress tests
Author(s) -
V. K. Tashchuk,
Oleksandr Hinhuliak,
П. Р. Іванчук
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.3.71.2014.155
Subject(s) - medicine , subclinical infection , ejection fraction , ventricle , cardiology , atorvastatin , treadmill , stress echocardiography , heart failure , coronary artery disease
In order to investigate the efficiency of a statin therapy (group 1, atorvastatin) and metabolic treatment (group 2, trimetazidine and MagneB6) 164 patients with signs of subclinical atherosclerosis were examined depending on an increase of intima-media thickness more than 0.9 mm in conditions of the pair echocardiography and stress tests (treadmill) with long follow-up observation (3 months and 1 year). Evaluation of the remodeling process in both treatment groups (statin/metabolic therapy) indicates a tendency, after 3 months of treatment, to increase the number of cases withincreased ejection fraction (EF) in group 1 (p 0,1) with the increase in the incidence of concentric remodeling of the left ventricle twice as often in group 2 (p>0,05), three times – in 3 months (p>0,5) after 1 year (p 0,5) with an increase after 1 year (p<0,05). Thus, the differences in influence of statin therapy and metabolic treatment on the parameters of central haemodynamics and response to stress tests for subclinical atherosclerosis have been established.