Open AccessEvaluation of control over the bronchial asthma in period of clinical well-being in teenagers depending on the severity of the bronchial inflammation
Author(s) -
Olga Shakhova,
I. B. Sichkar
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.2.70.2014.86
Subject(s) - asthma , medicine , bronchial hyperresponsiveness , exhaled air , inflammation , gastroenterology , pediatrics , respiratory disease , lung , toxicology , biology
At the basis of a complex examination of 63 adolescents it was revealed, that the signs of local inflammation in the bronchi and the increase of their nonspecific hyperresponsiveness remained in some of patients with asthma during the clinical well-being period with the absence of clinical symptoms. It was shown that the lower than 40.0 mmol/l content of nitrogen monoxide metabolites in the condensate of exhaled air increases the likelihood of retention of control: relative risk = 4,3 (while assessing the level of control by the ACT questionnaire) and 5,5 – in the evaluation of control level by the GINA questionnaire. Due to this the basic therapy is effective in almost every child, because the minimal number of patients needed to be treated to obtain a positive result is 1,3, according to ACT and GINA tests.