Open AccessSome aspects of pathogenesis of erosive-ulcerous gastric lesions in liver cirrhosis patients
Author(s) -
N. M. Palibroda,
О. І. Федів
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.2.70.2014.76
Subject(s) - cirrhosis , medicine , von willebrand factor , pathogenesis , portal hypertension , gastroenterology , tumor necrosis factor alpha , pathology , gastric mucosa , stomach , platelet
Von Willebrand factor, tumor necrosis factor-α levels and portal bloodstream were examined in 47 patients with liver cirrhosis and 8 apparently healthy persons. The increase of von Willebrand factor and tumor necrosis factor-α levels were found to lead to the development of erosive-ulcerative lesions of gastric mucosa. The abnormalities of portal resistance, von Willebrand factor and TNF-α are interrelated data which play a certain role in occurrence of erosive-ulcerative lesions of gastric mucosa in patients with liver cirrhosis.