Open AccessEarly and delayed reaction of temporal lobe cells of rats’ cerebral hemisphere to ischemia-reperfusion lesion
Author(s) -
Т. I. Kmet
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.2.70.2014.64
Subject(s) - ischemia , temporal lobe , lesion , cerebral cortex , lobe , cortex (anatomy) , neuron , medicine , neuroscience , pathology , anatomy , biology , epilepsy
It has been established that brain cell density is significantly reduced in the temporal lobe after a 20-minute carotid ischemia and one-hour reperfusion. Density and fraction of carotid cells of the temporal lobe with signs of apoptosis increase significantly on the 12th day of the study, due to reducing the number of neurons and especially glial cells. Ischemia-reperfusion lesion of the cerebral cortex in the investigated lobe leads to the most expressed disorders of neuron’s morphometric parameters both in the early and late period of ischemia-reperfusion.