Open AccessAchieving target blood pressure levels in patients with hypertension combined with comorbid type 2 diabetes after a standard multimodelity therapy
Author(s) -
O. І. Afanasiuk
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.2.70.2014.55
Subject(s) - medicine , ramipril , blood pressure , cardiology , diabetes mellitus , type 2 diabetes , nebivolol , diabetic cardiomyopathy , heart failure , endocrinology , cardiomyopathy
More than 80 % of patients with diabetes suffer from arterial hypertension. The combination of these two diseases increase the risk of premature death and disability in patients. The study involved 24 patients with essential hypertension stage II, II and III degree combined with diabetes type II, moderate severity in a state of subcompensation. A combination therapy with ramipril and nebivolol helped to reach the target pressure level after 1 month of treatment, as well as a significant decrease in myocardial stress by 27,28% (p<0,001), which is a sensitive indicator of changes in the heart. The treatment, being a safe option, significantly improved diastolic function of the heart and had a positive effect on lipid and carbohydrate metabolism.