Open AccessDifferentiated combined therapy of polycystic ovary syndrome for patients with obesity
Author(s) -
Y. V. Onyshchenko,
N. N. Rozhkovska
Publication year - 2014
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xviii.1.69.2014.19
Subject(s) - polycystic ovary , metformin , medicine , ovulation , body mass index , luteinizing hormone , insulin resistance , pathognomonic , infertility , obesity , gynecology , endocrinology , hormone , insulin , pregnancy , biology , disease , genetics
Obesity is one of pathognomonic symptoms of polycystic ovary syndrome (PCOS). According to different data sources its frequency among patients with PCOS ranges from 45 to 50 %. Efficiency of differentiated complex treatment of patients with PCOS is studied with taking body mass index (BMI) into account. Obtained data show positive effect of combined infertility treatment that included Metformin for insulin resistance correction as menstrual function and ovulation normalization in 58,7 % of patients with PCOS. Treatment with Metformin results in normalization of luteinizing hormone level which has explicit correlation with risk of 1st trimester miscarriages.