Open AccessClozapine detection in case of a forensic-medical examination of corpses: circumstances of death, anamnestic data, toxicological information
Author(s) -
O. V. Veselkina,
В. А. Клевно,
Н. А. Крупина,
V. U. Kaschanov
Publication year - 2013
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xvii.3.67.2013.119
Subject(s) - clozapine , forensic toxicology , medicine , alcohol consumption , forensic science , psychiatry , medical emergency , alcohol , schizophrenia (object oriented programming) , biology , chemistry , biochemistry , chromatography , veterinary medicine
Cases of poisonings, involving the medical agent - «clozapine» (syn. azaleptin, leponex) occur more often in the forensic-medical practice. Taking into account that such poisonings occur most frequently in criminal circumstances, they take on a special significance for a forensic-medical examination. Meanwhile, there are only few publications on the toxicologies of poisonings with clozapine, both alone and in combination with other substances, especially with alcohol. The authors have carried out a pilot study of 100 cases of death, in which during a forensic chemical examination of the blood and internal organs, clozapine was detected. Criminal proceedings were instituted and a criminal intake of clozapine was corroborated in 27 cases out of 100 selected cases. A major part of the observations was represented by men of employable age in whom alcohol was detected in the blood and urine that corresponded to different degrees of alcoholic intoxication. In these cases when clozapine was quantified, its concentration was therapeutic, a little seldom toxic.