Open AccessThe effect of the cultural medium and a mycelium extract of the mushroom Leucoagaricus macrorhizus on oxygen-dependent metabolism of peritoneal macrophages of mice
Author(s) -
O. V. Makarenko,
Mariia Rudyk,
В. В. Позур,
М. М. Сухомлин,
В. М. Святецька,
R. S. Dovgyi
Publication year - 2013
Publication title -
bukovinsʹkij medičnij vìsnik
Language(s) - English
Resource type - Journals
eISSN - 2413-0737
pISSN - 1684-7903
DOI - 10.24061/2413-0737.xvii.1.65.2013.16
Subject(s) - mycelium , mushroom , metabolism , oxygen , biology , microbiology and biotechnology , biochemistry , chemistry , food science , botany , organic chemistry
The effect of the cultural medium and an extract of mycelium of the Leucoagaricus macrorhizus mushroom on the oxygen dependent metabolism of peritoneal macrophages of mice has been investigated. It has been shown that the cultural medium influenced on the indices of the oxygen dependent metabolism of the phagocytic cells under study. The greatest effect was demonstrated by the cultural medium in a concentration of 100 and 200 μg/ml, raising the oxygendependent metabolism by 168 % and 143 % respectively. An extract of mycelium in a concentration of 50 μg/ml lowered the oxygen-dependent metabolism by 11 % compared to the control value, an addition of other concentrations did not cause reliable changes.