Open AccessTHE ROLE OF POLYMORPHISM OF HEAT SHOCK PROTEIN 70-2 GENE IN THE DEVELOPMENT OF VULVOVAGINITIS IN GIRLS OF BUKOVYNA REGION
Author(s) -
O. V. Bochkarova
Publication year - 2016
Publication title -
klìnìčna anatomìâ ta operativna hìrurgìâ
Language(s) - English
Resource type - Journals
eISSN - 1993-5897
pISSN - 1727-0847
DOI - 10.24061/1727-0847.15.4.2016.87
Subject(s) - gene , biology , polymorphism (computer science) , hsp70 , immune system , heat shock protein , pathophysiology , immunology , genetics , genotype , endocrinology
The paper presents analysis of А1267G polymorphism of HSP70-2 (id.: rs1061581) gene in the structure of sickness of girls suffering from vulvovaginitis. Polymorphism of HSP70 genes plays very important role in working of the immune system. It can be one of the important reasons of the genetically-provoked disregulation of inflammatory reaction. This will enable to present the scientific conception of pathophysiologic mechanisms of the development of vulvovaginitis.