Open AccessCORRELATION OF SERUM CRP & LACTATE AS AN EARLY PREDICTOR OF STRANGULATION IN ACUTE ABDOMEN
Author(s) -
Taimur Saleem,
Samaksh Giri,
Shadab Asif,
Brijesh Rathore
Publication year - 2020
Publication title -
era's journal of medical research
Language(s) - English
Resource type - Journals
eISSN - 2394-5222
pISSN - 2348-9839
DOI - 10.24041/ejmr2020.31
Subject(s) - abdomen , medicine , acute abdomen , predictive value , cutoff , c reactive protein , gastroenterology , complication , surgery , inflammation , physics , quantum mechanics
Strangulation in acute abdomen is one of the dangerous complication in patients of acute abdomen and early diagnosis is necessary for prevention of mortality. Present study was aimed to find whether serum C-Reactive Protein (CRP) and Serum Lactate can be used as early predictor for strangulation in cases of acute abdomen. A total of 75 patients with acute abdomen were included in the study. The serum CRP and Lactate values were measured preoperatively and correlated with intraop findings postoperatively. ROC curve was drawn and cutoff value for prediction of strangulation and mortality based on which diagnostic value was calculated. At cutoff level of 45.5 mg/L, CRP was 85.0% sensitive and 85.7% specific with positive and negative predictive values of 87.2% & 83.3% for prediction of strangulation in acute abdomen while sensitivity, specificity, PPV and NPV of Serum lactate was 100.0%, 91.4% 93.0% & 100.0% respectively using cutoff value ≥23.5mg/dl. Serum CRPand Lactate could be useful markers in predicting strangulation in cases of acute abdomen.