Open AccessRole of Growth Factors-Rich Plasma, Gel and Membrane in Dermal Wound Healing and Injured Tissue Restoration and Regeneration
Author(s) -
Tariq Mehmood Dar,
Kashif Ali Samin
Publication year - 2021
Publication title -
european journal of medical and health sciences
Language(s) - English
Resource type - Journals
ISSN - 2593-8339
DOI - 10.24018/ejmed.2021.3.6.1105
Subject(s) - wound healing , platelet rich plasma , regeneration (biology) , medicine , wound care , tissue repair , surgery , platelet , immunology , biomedical engineering , microbiology and biotechnology , biology
Background: The socioeconomic burden on society grows as the incidences of chronic age-related degenerative diseases increase which demand extensive wound care as well. To speed up the healing of cutaneous wounds, new wound healing treatments must be researched, trialed & developed. Regeneration therapies are gaining popularity since they are less invasive than other treatments.Method: Published research paper have been reviewed to develop a concept and analyze the role of Platelet-rich plasma (PRP) and Growth factors-rich plasma in speedy wound healing and tissue regeneration. Three patients with diabetic ulcers have been selected and applied Growth factors-rich plasma and membrane treatment on weekly basis and analyzed the results. Results: Growth factors-rich plasma injection and membrane application on wound have produced remarkable wound healing outcome within 3 to 6 applications with new vascularization and re-epithelialization. Conclusion: Growth factors-rich plasma and membrane application on wound gained favor as a wound-healing therapy due to its constituents which have remarkable potential to speed up the injured tissue repair and regeneration. The release of cytokines with platelet-derived growth molecules enveloped in alpha-granule, promote & facilitate wound healing.