Open AccessHypothalamic Hamartoma Revealed by Precocious Puberty in Girls: About A New Case
Author(s) -
S. Aminou,
A. Gaouzi,
Z. Imane
Publication year - 2021
Publication title -
european journal of medical and health sciences
Language(s) - English
Resource type - Journals
ISSN - 2593-8339
DOI - 10.24018/ejmed.2021.3.4.965
Subject(s) - hypothalamic hamartoma , precocious puberty , medicine , central precocious puberty , girl , hamartoma , bone age , pediatrics , endocrinology , hormone , pathology , psychology , developmental psychology
Precocious puberty is a multifactorial process whose diagnosis is based, first of all, on the clinic but also on the realization of the bone age, the pelvic ultrasound and the cerebral IRM. Moreover, the GnRH test constitutes the cornerstone to highlight a premature activation of the Hypothalamo-hypophyseal axis. We report the case of a 3-year-old girl admitted for exploration of precocious puberty. The central origin was confirmed by a GnRH test with a peak reaching 45 mIU/L. A hypothalamohypophyseal MRI was performed, showing a mass consistent with a hypothalamic hamartoma. Treatment with GnRH analogues is the treatment of choice for central precocious puberty.