Open AccessRare Case Report of Primary Gastric Melanoma
Author(s) -
K. Ashwini,
Deepa Mahesh,
M. S. Sandeep
Publication year - 2021
Publication title -
european journal of medical and health sciences
Language(s) - English
Resource type - Journals
ISSN - 2593-8339
DOI - 10.24018/ejmed.2021.3.2.763
Subject(s) - curvatures of the stomach , medicine , melena , eosinophilic , melanoma , biopsy , pathology , immunohistochemistry , stomach , dermatology , cancer research
Gastric melanomas are usually metastatic, and primary is almost rare entity.
Present case is a rare malignant melanoma of the gastric region with barely reported cases in the literature. A 65 year old male presented with pain abdomen and melena He was evaluated with relevant investigation. UGI endoscopy and PETCT shows large polypoidal irregular gastric mass in the proximal curvature extending upto gastroesophageal junction. Endoscopic biopsy a ulcero-infiltrating tumour, Individual cells are large, round, having moderately pleomorphic, hyperchromatic nuclei with prominent eosinophilic nucleoli and moderate eosinophilic cytoplasm. Immunohistochemistry of S100 and HMB45 was positive and negative for CK7 and CK20.
Early diagnosis of primary gastric melanoma allows for better prognosis of the patient from the right intervention.