Open AccessPrimary familial brain calcification: a clinical case
Author(s) -
Ю. А. Малышенко,
И. В. Сороко,
Д. В. Кобер,
Р. С. Богачев,
А. Е. Митюков
Publication year - 2019
Publication title -
fundamentalʹnaâ i kliničeskaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2542-0941
pISSN - 2500-0764
DOI - 10.23946/2500-0764-2019-4-3-128-132
Subject(s) - calcification , basal ganglia , medicine , magnetic resonance imaging , caudate nucleus , dentate nucleus , calcinosis , disease , pathology , radiology , central nervous system , cerebellum
Primary familial brain calcification (familial idiopathic basal ganglia calcification, Fahr’s disease) is a rare neurodegenerative syndrome characterised by a symmetrical bilateral calcification in the basal ganglia, dentate nucleus, cerebral cortex, and other regions of the brain. The widespread use of multislice computed tomography and magnetic resonance imaging increased the number of diagnosed cases, yet neither causes nor efficient treatment of this disease are known to date. Due to variable symptoms, primary familial brain calcification can resemble multiple neurological, mental, and endocrine disorders. Here we describe a case of a 38-year-old woman where timely multislice computed tomography led to the proper diagnosis and successful treatment.