Open AccessUnexpected death due to eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
Author(s) -
Inés Landín,
Eneko Barbería,
Concepción Dasi,
Josep ArimanyManso
Publication year - 2019
Publication title -
anales del sistema sanitario de navarra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.175
H-Index - 23
eISSN - 2340-3527
pISSN - 1137-6627
DOI - 10.23938/assn.0395
Subject(s) - medicine , granulomatosis with polyangiitis , eosinophilic , eosinophilia , necrotizing vasculitis , eosinophilic pneumonia , vasculitis , abdominal pain , asthma , dermatology , pathology , disease , gastroenterology , immunology , respiratory disease , lung
Eosinophilic granulomatosis with polyangiitis (EGPA), or Churg-Strauss syndrome, is a rare disease characterized by disseminated necrotizing vasculitis with extravascular granulomas occurring among patients with asthma and tissue eosinophilia. Clinically, it presents in various ways and progresses in three phases: prodromic (asthma and rhino-sinusitis), eosinophilic (peripheral eosinophilia and organ involvement), and vasculitic (clinical manifestations due to small vessel vasculitis). The differential diagnosis of EGPA principally includes eosinophilic and vasculitic disorders, early treatment is needed to avoid a fatal outcome. We present the case report of a 38-year-old male with a history of asthma. After a month-and-a-half of progressive weakness, no fever, diarrhea, vomiting and abdominal pain associated with weight loss, he was diagnosed of intestinal parasitosis. He later died of a massive myocardial necrosis due to EGPA with multiple organs affected.