Pemberitahuan Retraksi Artikel: Pengaruh Pemberian Terapi Tambahan Curcuma longa dan Boswellia serrata pada NSAID Terhadap Aktivitas Fungsional pada Pasien Osteoarthritis

Background: Osteoarthritis (OA) is a chronic disease that causes joint pain, stiffness, and swelling. The knee is the most affected joint in osteoarthritis. A common therapy that often used for osteoarthritis patients is NSAIDs, but previous study showed that satisfactory pain control cannot be achieved with NSAIDs alone so that additional analgesic therapy is needed. Some previous studies showed the extracts of Curcuma longa and Boswellia serrata were promising in reducing pain and do not cause serious side effects in osteoarthritis patients. Obejctive: to measure the effect of additional therapy Curcuma longa and Boswellia serrata to NSAIDs on functional activities in knee osteoarthritis patients. Methods: The type of this research is cross-sectional involving 71 patients. This study uses secondary data taken from previous RCT studies by completing questionnaires to determine the WOMAC score of osteoarthritis patients at Bethesda Hospital and Panti Rapih Hospital in Yogyakarta. The treatment used were CB extract (350 mg Curcuma longa and 150 mg Boswellia serrata) and NSAIDs (400 mg Ibuprofen or 50 mg sodium diclofenac). Data were analyzed statistically using the licensed SPSS program with the Wilcoxon test and the Mann-Whitney test. Results: The reduction of WOMAC scores was superior in the NSAIDs group with Curcuma longa and Boswellia serrata after being given therapy for 4 weeks but not significant (p=0.372). Conclusion: The giving of additional therapy Curcuma longa and Boswellia serrata to NSAIDs had the same effect as NSAIDs in increasing functional activities in osteoarthritis patients.